Description

tert-Butyl 4-(2-Aminopyrimidin-4-yl)piperidine-1-carboxylate is a high-purity, protected piperidine derivative featuring a key aminopyrimidine pharmacophore. This compound is a critical building block (intermediate) in modern pharmaceutical research and development, valued for its precise molecular architecture. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors for oncology and other therapeutic areas.
• Chemical Biology Research: Used as a scaffold or probe in the study of protein-ligand interactions and target identification.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: Employed in the contract manufacturing of complex molecules for preclinical and clinical trial materials.
• Academic Research: Utilized in university and institutional labs for novel synthetic methodology development and drug discovery projects.

Basic Information

Product Name	tert-Butyl 4-(2-Aminopyrimidin-4-yl)piperidine-1-carboxylate
CAS No.	1398511-11-9
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	1-Boc-4-(2-aminopyrimidin-4-yl)piperidine; 4-(2-Aminopyrimidin-4-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(2-aminopyrimidin-4-yl)piperidine-1-carboxylate; 1,1-Dimethylethyl 4-(2-amino-4-pyrimidinyl)-1-piperidinecarboxylate; 4-(2-Aminopyrimidin-4-yl)piperidine-1-carboxylic acid tert-butyl ester; BOC-4-(2-aminopyrimidin-4-yl)piperidine; CAS 1398511-11-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Aminopyrimidin-4-yl)piperidine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.