Description

6-Hydroxy-D-Tryptophan is a specialized, non-proteinogenic amino acid derivative of D-tryptophan. This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its role as a precursor in the biosynthesis of complex indole alkaloids and as a potential chiral building block. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, metabolic pathway studies, and the synthesis of novel therapeutic agents. Its high purity and defined stereochemistry are critical for ensuring reproducible experimental and developmental outcomes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel central nervous system (CNS) active drugs and serotonin pathway modulators.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis (e.g., tryptophan metabolism), and neurotransmitter research.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related compounds via HPLC or LC-MS.
• Precursor for Alkaloid Synthesis: Acts as a starting material in the organic synthesis of complex natural products and indole-based alkaloids for pharmacological screening.
• Nutraceutical Research: Investigated for its potential metabolic roles in advanced dietary supplement formulations and clinical nutrition studies.

Basic Information

Product Name	6-Hydroxy-D-Tryptophan
CAS No.	1398507-94-2
Molecular Formula	C₁₁H₁₂N₂O₃
Molecular Weight	220.23 g/mol
Synonyms	(R)-2-Amino-3-(6-hydroxy-1H-indol-3-yl)propanoic acid; D-6-HTP; 6-Hydroxy-DL-tryptophan (related); 6-OH-D-Trp; 6-Hydroxy-(R)-tryptophan; 6-Hydroxytryptophan, D- isomer; 6-Hydroxy-D-TRP; 6-Hydroxy-D-Trypt
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-D-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and development purposes. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.