Description

4-(4-Amino-6-Chloropyrimidin-2-Ylamino)Benzonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique pyrimidine-benzonitrile hybrid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical producers seeking a reliable building block for heterocyclic chemistry. The material is supplied with full analytical documentation to support stringent quality requirements.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides and fungicides containing pyrimidine motifs.
• Chemical Biology: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized chemical entities.
• Material Science: Potential precursor for the development of organic electronic materials and ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(4-Amino-6-Chloropyrimidin-2-Ylamino)Benzonitrile
CAS No.	1398507-08-8
Molecular Formula	C11H7ClN6
Molecular Weight	258.67 g/mol
Synonyms	4-[(4-Amino-6-chloro-2-pyrimidinyl)amino]benzonitrile; 4-[(4-Amino-6-chloropyrimidin-2-yl)amino]benzonitrile; 4-(4-Amino-6-chloro-pyrimidin-2-ylamino)-benzonitrile; 2-[(4-Cyanophenyl)amino]-6-chloro-4-pyrimidinamine; 6-Chloro-N2-(4-cyanophenyl)pyrimidine-2,4-diamine; Benzonitrile, 4-[(4-amino-6-chloro-2-pyrimidinyl)amino]-; 1398507-08-8
EINECS	Contact for details

Quality Control

Our 4-(4-Amino-6-Chloropyrimidin-2-Ylamino)Benzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.