Description

Fmoc-Dl-Ethionine CAS NO 1396988-59-2 is a protected amino acid derivative featuring the 9-fluorenylmethoxycarbonyl (Fmoc) group, a cornerstone reagent in modern solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled, sequential assembly of complex peptides by providing orthogonal protection for the amino acid's functional groups. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who are developing novel peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected building block for the automated or manual synthesis of custom peptide sequences.
• Pharmaceutical Research: Incorporation into peptide drug candidates for the treatment of metabolic disorders, cancers, and infectious diseases.
• Bioconjugation & Probe Development: Used to introduce the ethionine moiety, a methionine analog, into peptides for biochemical studies, metabolic labeling, or as a handle for further chemical modification.
• Combinatorial Chemistry Libraries: Serves as a versatile monomer for generating diverse peptide libraries for high-throughput screening in drug discovery.
• Academic & Industrial R&D: Fundamental research tool in biochemistry and molecular biology for studying protein structure, function, and post-translational modifications.
• Production of Reference Standards: Synthesis of high-purity peptide standards for analytical method development and quality control in regulated environments.

Basic Information

Product Name	Fmoc-Dl-Ethionine
CAS No.	1396988-59-2
Molecular Formula	C22H25NO5S
Molecular Weight	415.50 g/mol
Synonyms	Fmoc-DL-Ethionine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-DL-ethionine; N-Fmoc-DL-ethionine; DL-2-Amino-4-(ethylthio)butyric acid N-fluorenylmethoxycarbonyl derivative; Fmoc-ethylhomoCys; Fmoc-Ethionine, DL-; N-(9-Fluorenylmethoxycarbonyl)-DL-ethionine; (RS)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(ethylthio)butanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Dl-Ethionine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.