Description

2-[(2-Chloro-4-Pyrimidinyl)Amino]Benzamide is a high-purity, advanced pharmaceutical intermediate with a distinct pyrimidine-benzamide core structure. This compound is a critical building block in the research and development of targeted small-molecule therapeutics, particularly kinase inhibitors. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop novel drug candidates for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology research.
• Medicinal Chemistry R&D: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a critical starting material for scaling up the production of active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in the development of assay probes and tool compounds for studying specific biological pathways.
• Custom Synthesis: A foundational compound for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules for clients.

Basic Information

Product Name	2-[(2-Chloro-4-Pyrimidinyl)Amino]Benzamide
CAS No.	1395886-42-6
Molecular Formula	C11H9ClN4O
Molecular Weight	248.67 g/mol
Synonyms	2-[(2-Chloro-4-pyrimidinyl)amino]benzamide; 2-(2-Chloropyrimidin-4-ylamino)benzamide; N-(2-Chloropyrimidin-4-yl)anthranilamide; Benzamide, 2-[(2-chloro-4-pyrimidinyl)amino]-; 1395886-42-6; 2-Amino-N-(2-chloropyrimidin-4-yl)benzamide; 2-[(2-Chloro-pyrimidin-4-yl)amino]-benzamide
EINECS	Contact for details

Quality Control

Our 2-[(2-Chloro-4-Pyrimidinyl)Amino]Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.