Description

3,5-Dichloro-2-Fluoroaniline is a halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which enables the precise introduction of functional groups for creating complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and anti-infective applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where its halogenated structure contributes to biological activity.
• Material Science: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments.
• Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for constructing biaryl systems.

Basic Information

Product Name	3,5-Dichloro-2-Fluoroaniline
CAS No.	1394838-36-8
Molecular Formula	C6H4Cl2FN
Molecular Weight	180.01 g/mol
Synonyms	2-Fluoro-3,5-dichloroaniline; 3,5-Dichloro-2-fluoro-benzenamine; Benzenamine, 3,5-dichloro-2-fluoro-; 3,5-Dichloro-2-fluorophenylamine; 2-Amino-1,3-dichloro-4-fluorobenzene; 1-Amino-2,4-dichloro-5-fluorobenzene; 3,5-Dichloro-2-fluoroaniline (DC2FA)
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-2-Fluoroaniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with relevant regulatory frameworks such as REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.