Description

Ethyl 3-Bromopyrazolo[1,5-A]Pyrimidine-2-Carboxylate is a high-value brominated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the development of new active ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel pyrazolopyrimidine scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, anticancer agents, and other small molecule therapeutics targeting the pyrazolopyrimidine pharmacophore.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require the specific bromine substitution for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating labeled compounds or molecular probes to study biological pathways and enzyme functions.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, heteroaromatic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this specialized brominated ester.

Basic Information

Product Name	Ethyl 3-Bromopyrazolo[1,5-A]Pyrimidine-2-Carboxylate
CAS No.	1394004-05-7
Molecular Formula	C9H8BrN3O2
Molecular Weight	270.08 g/mol
Synonyms	Ethyl 3-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate; 3-Bromo-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid ethyl ester; 2-Carbethoxy-3-bromopyrazolo[1,5-a]pyrimidine; Ethyl 3-bromo-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylate; 1394004-05-7; 3-Bromopyrazolo[1,5-a]pyrimidine-2-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 3-Bromopyrazolo[1,5-A]Pyrimidine-2-Carboxylate adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized by modern analytical techniques including NMR, HPLC, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We operate under a quality management system and can support development projects requiring GMP (Good Manufacturing Practice) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.