Description

tert-Butyl Pyrazolo[1,5-A]Pyrimidin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its pyrazolopyrimidine core structure. This compound is of significant commercial value as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and kinase inhibitor research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors.
• Oncology Research: Serves as a scaffold for developing novel compounds targeting specific cancer pathways and protein kinases.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Biochemical Tool Compound: Can be utilized in the development of probes for studying enzyme function and cellular signaling mechanisms.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of bespoke molecules for clinical trials.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	tert-Butyl Pyrazolo[1,5-A]Pyrimidin-3-Ylcarbamate
CAS No.	1394003-66-7
Molecular Formula	C11H14N4O2
Molecular Weight	234.26 g/mol
Synonyms	tert-Butyl pyrazolo[1,5-a]pyrimidine-3-carboxylate; 3-(((tert-Butoxy)carbonyl)amino)pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidin-3-yl-carbamic acid tert-butyl ester; BOC-Pyrazolopyrimidine; tert-Butyl N-(pyrazolo[1,5-a]pyrimidin-3-yl)carbamate; 1394003-66-7; tert-Butyl 3-aminopyrazolo[1,5-a]pyrimidine-3-carboxylate (common misnomer)
EINECS	Contact for details

Quality Control

Our tert-Butyl Pyrazolo[1,5-A]Pyrimidin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.