Description

6-Chloro-3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potent kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its versatile pyrazolopyrimidine core.
• Biochemical Probe Development: Serves as a scaffold for creating tool compounds to study specific enzyme pathways and biological targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery pipelines for global clients.
• Academic Research: Utilized in university laboratories for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-Chloro-3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	1393547-40-4
Molecular Formula	C5H2ClIN4
Molecular Weight	295.45 g/mol
Synonyms	6-Chloro-3-iodo-1H-pyrazolo[3,4-d]pyrimidine; 3-Iodo-6-chloro-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 6-chloro-3-iodo-; 6-Chloro-3-iodopyrazolo[3,4-d]pyrimidine; 1393547-40-4; CAS 1393547-40-4
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.