Description

5-Bromo-2-[1,3]Dioxolan-2-Yl-Pyrimidine CAS NO 1392803-06-3 is a high-purity, heterocyclic organic building block featuring a brominated pyrimidine core protected by a dioxolane group. This compound is critical for enabling complex synthetic pathways in advanced pharmaceutical and agrochemical research, offering a reactive handle for further functionalization. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for creating functionalized ligands, organic semiconductors, and liquid crystals.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Item	Detail
Product Name	5-Bromo-2-[1,3]Dioxolan-2-Yl-Pyrimidine
CAS No.	1392803-06-3
Molecular Formula	C7H7BrN2O2
Molecular Weight	231.05 g/mol
Synonyms	5-Bromo-2-(1,3-dioxolan-2-yl)pyrimidine; 2-(5-Bromopyrimidin-2-yl)-1,3-dioxolane; 5-Bromo-2-(1,3-dioxolan-2-yl)pyrimidine; 5-Bromo-2-pyrimidinyl-1,3-dioxolane; 1392803-06-3; 5-Bromo-2-(dioxolan-2-yl)pyrimidine; Pyrimidine, 5-bromo-2-(1,3-dioxolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-[1,3]Dioxolan-2-Yl-Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.