Description

3-(4-Methoxybenzyl)-4A,5-Dihydro-1H-Pyrrolo[3,2-D]Pyrimidine-2,4(3H,7Ah)-Dione is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting kinase inhibition and other therapeutic pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in drug discovery, process development, and the production of targeted therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and commercial production of novel drug candidates.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug-like properties and efficacy.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale synthesis for new chemical entities (NCEs).
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays and target validation studies.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.

Basic Information

Item	Details
Product Name	3-(4-Methoxybenzyl)-4A,5-Dihydro-1H-Pyrrolo[3,2-D]Pyrimidine-2,4(3H,7Ah)-Dione
CAS No.	1392484-74-0
Molecular Formula	C15H15N3O3
Molecular Weight	285.30 g/mol
Synonyms	3-[(4-Methoxyphenyl)methyl]-4a,5-dihydro-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,7aH)-dione; 3-(4-Methoxybenzyl)-4a,5-dihydro-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,7aH)-dione; Pyrrolo[3,2-d]pyrimidine-2,4(1H,3H)-dione, 3-[(4-methoxyphenyl)methyl]-4a,5-dihydro-; Fused Pyrrolopyrimidine Derivative; Kinase Inhibitor Intermediate; CAS 1392484-74-0
EINECS	Contact for details

Quality Control

Our 3-(4-Methoxybenzyl)-4A,5-Dihydro-1H-Pyrrolo[3,2-D]Pyrimidine-2,4(3H,7Ah)-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring material for research, development, and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The material may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.