Description

(5-Hydroxy-Pyrimidin-2-Ylmethyl)-Carbamic Acid tert-Butyl Ester (Wx649057) is a high-purity, protected pyrimidine derivative of significant interest in advanced organic synthesis. This compound matters as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile scaffold for medicinal chemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need this intermediate for constructing complex molecules, particularly in the areas of antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly in antiviral and anticancer research pipelines.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its modifiable pyrimidine core and protected functional groups.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex heterocyclic compounds and specialty chemicals.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and diagnostic applications, leveraging its reactive sites.
• Agrochemical Research: Employed in the research and development of new agrochemicals, such as herbicides or fungicides, where pyrimidine structures are common.

Basic Information

Product Name	(5-Hydroxy-Pyrimidin-2-Ylmethyl)-Carbamic Acid tert-Butyl Ester (Wx649057)
CAS No.	1391732-63-0
Molecular Formula	C11H17N3O3
Molecular Weight	239.27 g/mol
Synonyms	tert-Butyl N-[(5-hydroxypyrimidin-2-yl)methyl]carbamate; N-Boc-2-(aminomethyl)-5-hydroxypyrimidine; 2-((tert-Butoxycarbonylamino)methyl)-5-hydroxypyrimidine; 5-Hydroxy-2-((((2-methyl-2-propanyl)oxy)carbonylamino)methyl)pyrimidine; Wx649057; (5-Hydroxy-2-pyrimidinylmethyl)carbamic acid 1,1-dimethylethyl ester; Boc-5-hydroxy-2-pyrimidinylmethylamine
EINECS	Contact for details

Quality Control

Our (5-Hydroxy-Pyrimidin-2-Ylmethyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.