Description

(1S)-1-[4-(Trifluoromethyl)Phenyl]-Prop-2-En-1-Amine Hydrochloride is a chiral amine hydrochloride salt featuring a trifluoromethylphenyl group, a key structural motif in advanced pharmaceutical chemistry. This compound is valued for its role as a high-purity chiral building block and synthetic intermediate in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Chemical Research: Acts as a versatile building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of complex organic molecules.

Basic Information

Product Name	(1S)-1-[4-(Trifluoromethyl)Phenyl]-Prop-2-En-1-Amine Hydrochloride
CAS No.	1391528-41-8
Molecular Formula	C10H10ClF3N
Molecular Weight	236.64 g/mol
Synonyms	(S)-1-(4-(Trifluoromethyl)phenyl)allylamine hydrochloride; (1S)-1-[4-(Trifluoromethyl)phenyl]prop-2-en-1-amine hydrochloride; (S)-α-Methyl-4-(trifluoromethyl)benzeneethanamine hydrochloride; (S)-1-(4-Trifluoromethylphenyl)allylamine HCl; (S)-1-(4-(Trifluoromethyl)phenyl)-2-propen-1-amine hydrochloride; (S)-4-(Trifluoromethyl)benzylallylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1S)-1-[4-(Trifluoromethyl)Phenyl]-Prop-2-En-1-Amine Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.