Description

(1R)-1-[3-(Trifluoromethoxy)Phenyl]Butylamine Hydrochloride is a chiral amine derivative of significant interest in advanced organic synthesis. This compound matters as a high-purity building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific stereochemistry and trifluoromethoxy substituent are critical for bioactivity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Key chiral intermediate in the synthesis of pharmaceutical candidates, particularly for central nervous system (CNS) targets.
• Building block for the development of novel agrochemicals, including herbicides and fungicides.
• Precursor for the preparation of advanced ligands and catalysts used in asymmetric synthesis.
• Starting material for research into bioactive molecules containing the trifluoromethoxy pharmacophore.
• Intermediate in the custom synthesis of complex organic molecules for material science applications.
• Reference standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	(1R)-1-[3-(Trifluoromethoxy)Phenyl]Butylamine Hydrochloride
CAS No.	1391474-17-1
Molecular Formula	C11H14F3NO•HCl
Molecular Weight	269.69 g/mol
Synonyms	(R)-1-(3-(Trifluoromethoxy)phenyl)butan-1-amine hydrochloride; (1R)-1-[3-(Trifluoromethoxy)phenyl]butylamine HCl; (R)-α-Methyl-3-(trifluoromethoxy)benzenepropanamine hydrochloride; (R)-1-(3-(Trifluoromethoxyphenyl))butylamine hydrochloride; (R)-1-(3-Trifluoromethoxyphenyl)butylamine hydrochloride; (R)-3'-Trifluoromethoxyamphetamine hydrochloride; (R)-1-Amino-1-(3-trifluoromethoxyphenyl)butane hydrochloride
EINECS	Contact for details

Quality Control

Our (1R)-1-[3-(Trifluoromethoxy)Phenyl]Butylamine Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.