Description

3-o-Methyl-L-Dopa 4-Sulfate is a chemically modified derivative of the amino acid L-Dopa, specifically sulfated at the 4-position and methylated at the 3-hydroxy group. This structural modification is critical for its role as a key metabolite and reference standard in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector who require high-purity biochemical intermediates. The compound is essential for metabolic pathway studies, analytical method development, and the synthesis of more complex therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and identification of metabolites in bioanalytical studies, particularly in pharmacokinetics and drug metabolism research.
• Biochemical Research: Serves as a crucial intermediate or substrate in enzymatic studies to investigate sulfation and methylation pathways related to neurotransmitter metabolism.
• Metabolite Synthesis: Employed in the organic synthesis of more complex drug metabolites for safety and efficacy testing during preclinical and clinical development phases.
• Diagnostic Development: Acts as a calibrator or control in the development of diagnostic assays, such as LC-MS/MS methods, for monitoring neurological and metabolic disorders.
• Academic Research: Used in university and institutional labs for fundamental research into Parkinson's disease, catecholamine biology, and phase II drug conjugation processes.

Basic Information

Product Name	3-o-Methyl-L-Dopa 4-Sulfate
CAS No.	1391393-86-4
Molecular Formula	C10H13NO7S
Molecular Weight	291.28 g/mol
Synonyms	3-Methoxy-L-tyrosine 4-Sulfate; L-3-O-Methyldopa 4-Sulfate; 3-OMD 4-Sulfate; (2S)-2-Amino-3-(4-sulfooxy-3-methoxyphenyl)propanoic acid; 4-Sulfooxy-3-methoxy-L-phenylalanine; 3-Methoxy-L-dopa 4-Sulfate Ester
EINECS	Contact for details

Quality Control

Every batch of 3-o-Methyl-L-Dopa 4-Sulfate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use in regulated environments. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.