Description

2-Chloro-8-Fluoroquinazoline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering precise reactivity for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Material Science: Acts as a building block for advanced organic electronic materials and functional polymers.
• Contract Research & Development (CRO/CMO): Supplied to service organizations for custom synthesis and library production for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploration of new chemical reactions.

Basic Information

Product Name	2-Chloro-8-Fluoroquinazoline
CAS No.	1388055-06-8
Molecular Formula	C8H4ClFN2
Molecular Weight	182.58 g/mol
Synonyms	8-Fluoro-2-chloroquinazoline; Quinazoline, 2-chloro-8-fluoro-; 2-Chloro-8-fluoro-quinazoline; 1388055-06-8; 2-Chloro-8-fluoroquinazoline; 8-Fluoro-2-chloro-quinazoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-Fluoroquinazoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.