Description

Benzenamine, 2-Fluoro-3-(trifluoromethoxy)-, hydrochloride (1:1) is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, makes it an essential intermediate for developing novel compounds with tailored properties. This product is primarily targeted at research and development laboratories and industrial manufacturers in the pharmaceutical and agrochemical sectors, where it is used to create active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and electronic materials.
• Chemical Research: Employed in academic and industrial R&D for exploring novel reaction pathways and creating compound libraries for high-throughput screening.
• Fluorine Chemistry: A valuable reagent for introducing fluorinated motifs into complex molecules, leveraging its reactive aniline functionality.

Basic Information

Product Name	Benzenamine, 2-Fluoro-3-(trifluoromethoxy)-, hydrochloride (1:1)
CAS No.	1386459-74-0
Molecular Formula	C7H6F4NO•HCl
Molecular Weight	235.58 g/mol
Synonyms	2-Fluoro-3-(trifluoromethoxy)aniline hydrochloride; 3-(Trifluoromethoxy)-2-fluoroaniline hydrochloride; 2-Fluoro-α,α,α-trifluoro-m-anisidine hydrochloride; 2-Fluoro-3-trifluoromethoxyaniline HCl; 2-Fluoro-3-(trifluoromethoxy)phenylamine hydrochloride; 1-Amino-2-fluoro-3-(trifluoromethoxy)benzene hydrochloride
EINECS	Contact for details

Quality Control

Our Benzenamine, 2-Fluoro-3-(trifluoromethoxy)-, hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.