Description

3-Fluoro-2-(Tetrahydrofuran-2-Yl)Aniline is a specialized fluorinated aniline derivative featuring a tetrahydrofuran ring, making it a valuable chiral building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure imparts specific biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atom and heterocyclic moiety enhance bioactivity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals and functional polymers, due to its aromatic and heterocyclic components.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes to study biological processes and enzyme mechanisms.

Basic Information

Product Name	3-Fluoro-2-(Tetrahydrofuran-2-Yl)Aniline
CAS No.	1384984-24-0
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	2-(3-Fluoro-2-aminophenyl)tetrahydrofuran; 2-(Tetrahydrofuran-2-yl)-3-fluoroaniline; 3-Fluoro-2-(tetrahydro-2-furyl)aniline; 2-Amino-6-fluorophenyl tetrahydrofuran; 3-Fluoro-2-(oxolan-2-yl)aniline; Benzenamine, 3-fluoro-2-(tetrahydro-2-furanyl)-; 1384984-24-0
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Tetrahydrofuran-2-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. The material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Light yellow to brown solid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.