Description

Pyrimidine, 2-(Chloromethyl)-5-Methyl-, Hydrochloride (1:1) is a high-purity, functionalized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive chloromethyl group, which enables efficient derivatization and incorporation into more complex molecular architectures. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyrimidine core is a common bioactive moiety.
• Chemical Research: Serves as a versatile precursor in academic and industrial laboratories for synthesizing libraries of compounds for screening and structure-activity relationship (SAR) studies.
• Material Science: Potential application in the synthesis of organic ligands for catalysts or functional polymers with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	Pyrimidine, 2-(Chloromethyl)-5-Methyl-, Hydrochloride (1:1)
CAS No.	1384430-75-4
Molecular Formula	C6H8Cl2N2
Molecular Weight	179.05 g/mol
Synonyms	2-(Chloromethyl)-5-methylpyrimidine hydrochloride; 5-Methyl-2-(chloromethyl)pyrimidine hydrochloride; 2-Chloromethyl-5-methylpyrimidine HCl; 5-Methyl-2-pyrimidinylmethyl chloride hydrochloride; (5-Methyl-2-pyrimidinyl)methyl chloride hydrochloride; 1384430-75-4; 2-(Chloromethyl)-5-methylpyrimidine HCl salt
EINECS	Contact for details

Quality Control

Every batch of Pyrimidine, 2-(Chloromethyl)-5-Methyl-, Hydrochloride (1:1) is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.