Description

3-(2-Amino-5-Bromo-1,6-Dihydro-6-Oxo-4-Pyrimidinyl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidinyl-benzoic acid hybrid structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, especially for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile functional groups.
• Protease Inhibitor Development: The molecular scaffold is valuable for designing inhibitors targeting specific enzymes.
• Kinase Inhibitor Synthesis: Serves as a core structure in the development of potential kinase inhibitors for cancer treatment.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.

Basic Information

Product Name	3-(2-Amino-5-Bromo-1,6-Dihydro-6-Oxo-4-Pyrimidinyl)Benzoic Acid
CAS No.	1383132-82-8
Molecular Formula	C11H8BrN3O3
Molecular Weight	310.11 g/mol
Synonyms	5-Bromo-2-amino-6-oxo-1,6-dihydro-4-pyrimidinebenzoic acid; 3-(2-Amino-5-bromo-6-oxo-1,6-dihydropyrimidin-4-yl)benzoic acid; Benzoic acid, 3-(2-amino-5-bromo-1,6-dihydro-6-oxo-4-pyrimidinyl)-; 4-(3-Carboxyphenyl)-5-bromo-2-amino-6-hydroxypyrimidine; 1383132-82-8; 3-(2-Amino-5-bromo-6-oxo-1H-pyrimidin-4-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-(2-Amino-5-Bromo-1,6-Dihydro-6-Oxo-4-Pyrimidinyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.