Description

2-Chloro-4-Amino-5-(Cyclopropyl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine core functionalized with chloro, amino, and cyclopropyl substituents. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of antiviral and anticancer agents, where its specific molecular architecture is leveraged for structure-activity relationship (SAR) studies and lead optimization.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel antiviral and anticancer drug candidates.
• Medicinal Chemistry Research: Used in SAR studies and lead compound optimization for new therapeutic targets.
• Agrochemical Development: Serves as a precursor in the research and production of advanced crop protection agents.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic systems.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	2-Chloro-4-Amino-5-(Cyclopropyl)Pyrimidine
CAS No.	1381933-37-4
Molecular Formula	C7H8ClN3
Molecular Weight	169.61 g/mol
Synonyms	5-(Cyclopropyl)-2-chloro-4-pyrimidinamine; 2-Chloro-5-cyclopropylpyrimidin-4-amine; 4-Amino-2-chloro-5-cyclopropylpyrimidine; 2-Chloro-4-amino-5-cyclopropylpyrimidine; 1381933-37-4; 5-Cyclopropyl-2-chloropyrimidin-4-amine; 4-Pyrimidinamine, 2-chloro-5-cyclopropyl-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Amino-5-(Cyclopropyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.