Description

L-Phenylalanine, 4-Cyclohexyl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is a specialized, protected amino acid derivative designed for advanced synthetic applications. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of novel peptide-based drugs and bioactive compounds.
• Peptidomimetic Research: Used to incorporate modified phenylalanine residues into peptide chains to enhance stability, bioavailability, and receptor binding affinity.
• Chemical Biology Probes: Serves as a building block for creating labeled or tagged peptides used in biochemical assays and diagnostic research.
• Process Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) under current Good Manufacturing Practice (cGMP) standards.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry projects and the development of new synthetic methodologies.

Basic Information

Product Name	L-Phenylalanine, 4-Cyclohexyl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	1381801-21-3
Molecular Formula	C30H31NO4
Molecular Weight	469.57 g/mol
Synonyms	Fmoc-4-cyclohexyl-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-cyclohexyl-L-phenylalanine; Fmoc-Cyh-Phe-OH; Fmoc-L-Phe(4-Cyclohexyl)-OH; N-α-Fmoc-4-cyclohexyl-L-phenylalanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-[4-(cyclohexyl)phenyl]propanoic acid
EINECS	Contact for details

Quality Control

Our production of this high-purity building block adheres to stringent quality protocols. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP-compliant applications and meet the exacting standards of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.