Description

2，2-Difluoro-2-(2-Methoxyphenyl)Ethan-1-Ol is a specialized fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring a difluoromethyl group adjacent to a hydroxyl on a methoxyphenyl scaffold, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where the introduction of fluorine atoms is a key strategy to modulate bioavailability, metabolic stability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in creating fluorinated analogs of bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where fluorination enhances lipophilicity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique solubility, surface energy, or chemical resistance properties.
• Organic Electronic Materials: Utilized in the synthesis of fluorinated organic semiconductors or charge-transport materials.
• Chemical Research & Development: Employed in academic and industrial R&D settings for methodology development and exploring new chemical spaces in fluoroorganic chemistry.

Basic Information

Product Name	2，2-Difluoro-2-(2-Methoxyphenyl)Ethan-1-Ol
CAS No.	1380202-51-6
Molecular Formula	C9H10F2O2
Molecular Weight	188.17 g/mol
Synonyms	2-(2-Methoxyphenyl)-2,2-difluoroethanol; 1-(2-Methoxyphenyl)-2,2-difluoroethan-1-ol; α,α-Difluoro-2-methoxybenzeneethanol; 2,2-Difluoro-1-(2-methoxyphenyl)ethanol; 2-Methoxy-α,α-difluorobenzeneethanol
EINECS	Contact for details

Quality Control

Our 2，2-Difluoro-2-(2-Methoxyphenyl)Ethan-1-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to cGMP principles and adherence to ISO 9001 standards underpin our reliable supply chain for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.