Description

3-(4-Fluorophenyl)Oxetan-3-Ol is a high-value oxetane derivative featuring a fluorinated aromatic ring, serving as a critical chiral building block in advanced organic synthesis. Its unique structure provides a versatile scaffold for constructing complex molecules with enhanced metabolic stability and binding affinity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of small-molecule drug candidates, especially in kinase inhibitor and CNS-targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorophenyl group can improve bioactivity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing specialty polymers with unique thermal and mechanical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological pathways and protein interactions.

Basic Information

Product Name	3-(4-Fluorophenyl)Oxetan-3-Ol
CAS No.	1379812-16-4
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	3-(4-Fluorophenyl)-3-hydroxyoxetane; 3-Hydroxy-3-(4-fluorophenyl)oxetane; 4-Fluoro-α-(2-hydroxyethyl)benzenemethanol; Oxetan-3-ol, 3-(4-fluorophenyl)-; 1379812-16-4
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)Oxetan-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.