Description

5-(Pentafluorothio)-1,3-Benzoxazole, 5-(Pentafluorosulphanyl)Benzo[D]Oxazole CAS NO 1379812-05-1 is a high-value, fluorinated heterocyclic building block characterized by its unique pentafluorosulfanyl (SF5) functional group. This compound is critical for advanced research and development, offering exceptional thermal stability, lipophilicity, and electronic properties that are highly sought after in modern synthetic chemistry. It is primarily utilized by pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and high-performance specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for developing new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in the synthesis of next-generation herbicides, fungicides, and insecticides, where the SF5 group enhances biological activity and environmental stability.
• Advanced Material Synthesis: Serves as a precursor for liquid crystals, organic semiconductors, and polymers requiring specific dielectric and thermal properties.
• Fluorine Chemistry & Catalysis: An important reagent in organofluorine chemistry for introducing the pentafluorosulfanyl moiety into complex molecular architectures.
• Ligand & Catalyst Design: Employed in the development of novel ligands for transition metal catalysis and asymmetric synthesis.
• Life Science Research: Used as a biochemical probe or a tag in PET (Positron Emission Tomography) tracer development due to the fluorine content.

Basic Information

Product Name	5-(Pentafluorothio)-1,3-Benzoxazole, 5-(Pentafluorosulphanyl)Benzo[D]Oxazole
CAS No.	1379812-05-1
Molecular Formula	C7H2F5NOS
Molecular Weight	243.16 g/mol
Synonyms	5-(Pentafluorosulfanyl)benzoxazole; 5-(SF5)-Benzoxazole; 1,3-Benzoxazole, 5-(pentafluorothio)-; 5-(Pentafluorosulphanyl)-1,3-benzoxazole; Benzo[d]oxazole, 5-(pentafluorosulfanyl)-; 5-(Pentafluorosulfanyl)-1,3-benzoxazole; 5-(Pentafluorosulfanyl)benzo[d]oxazole; 5-SF5-Benzoxazole
EINECS	Contact for details

Quality Control

Our 5-(Pentafluorothio)-1,3-Benzoxazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC-MS, NMR, and elemental analysis to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.