Description

Methyl [2-(Cyclopropylamino)-6-Oxo-1,4,5,6-Tetrahydropyrimidin-5-Yl]Acetate is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process optimization.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders or infectious diseases.
• Organic Synthesis Research: Serves as a versatile precursor for constructing complex tetrahydropyrimidinone derivatives in academic and industrial R&D laboratories.
• Process Chemistry: Used in route scouting and scale-up studies for the commercial manufacturing of target molecules.
• Contract Development and Manufacturing (CDMO): Supplied to CDMOs for the production of clinical trial materials and commercial APIs under GMP guidelines.

Basic Information

Product Name	Methyl [2-(Cyclopropylamino)-6-Oxo-1,4,5,6-Tetrahydropyrimidin-5-Yl]Acetate
CAS No.	1379811-77-4
Molecular Formula	C₁₀H₁₅N₃O₃
Molecular Weight	225.25 g/mol
Synonyms	5-(Methoxycarbonylmethyl)-2-(cyclopropylamino)-5,6-dihydro-1H-pyrimidin-6-one; Methyl 2-[(2-(cyclopropylamino)-6-oxo-1,4,5,6-tetrahydropyrimidin-5-yl)]acetate; 2-(Cyclopropylamino)-5-(2-methoxy-2-oxoethyl)-5,6-dihydro-1H-pyrimidin-6-one; CPAP Intermediate; CAS 1379811-77-4
EINECS	Contact for details

Quality Control

Our production of Methyl [2-(Cyclopropylamino)-6-Oxo-1,4,5,6-Tetrahydropyrimidin-5-Yl]Acetate adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability. All materials are supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material suitable for research use under standard laboratory conditions or higher grades developed in alignment with GMP principles for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.