Description

2-(Cyclopropylamino)-5,6-Dimethylpyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. Pharmaceutical R&D teams and fine chemical manufacturers need this material to develop and scale up production of next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyrimidine core for biological activity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in medicinal chemistry.
• Academic & Contract Research: Employed in research institutions and CROs for method development and exploratory synthesis projects.
• Material Science Applications: Potential use in the development of organic electronic materials and specialty polymers.

Basic Information

Product Name	2-(Cyclopropylamino)-5,6-Dimethylpyrimidin-4(3H)-One
CAS No.	1379811-68-3
Molecular Formula	C9H13N3O
Molecular Weight	179.22 g/mol
Synonyms	2-(Cyclopropylamino)-5,6-dimethyl-4(3H)-pyrimidinone; 5,6-Dimethyl-2-(cyclopropylamino)pyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 2-(cyclopropylamino)-5,6-dimethyl-; 2-Cyclopropylamino-5,6-dimethylpyrimidin-4-ol; CPAP Intermediate; Cyclopropylaminodimethylpyrimidinone
EINECS	Contact for details

Quality Control

Our 2-(Cyclopropylamino)-5,6-Dimethylpyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliability for demanding pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.