Description

Ethyl 7-Amino-2-Cyclobutyl[1,2,4]Triazolo-[1,5-A]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrimidine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in areas requiring sophisticated nitrogen-containing heterocyclic scaffolds.

Application

This specialized intermediate serves as a key precursor in several high-value synthetic pathways.

• Pharmaceutical Intermediate: Core building block for the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Integral in the multi-step synthesis of complex Active Pharmaceutical Ingredients, especially those containing fused triazole and pyrimidine rings.
• Biochemical Tool Compound: May be utilized in the development of probes for studying enzymatic or receptor-based biological processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	Ethyl 7-Amino-2-Cyclobutyl[1,2,4]Triazolo-[1,5-A]Pyrimidine-6-Carboxylate
CAS No.	1379811-62-7
Molecular Formula	C12H15N5O2
Molecular Weight	261.28 g/mol
Synonyms	Ethyl 7-amino-2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate; 7-Amino-2-cyclobutyl[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; 2-Cyclobutyl-7-amino-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; 1379811-62-7; Ethyl 7-amino-2-cyclobutyltriazolopyrimidine-6-carboxylate; 6-Carbethoxy-7-amino-2-cyclobutyl[1,2,4]triazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our production of Ethyl 7-Amino-2-Cyclobutyl[1,2,4]Triazolo-[1,5-A]Pyrimidine-6-Carboxylate adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.