Description

(1-Cyclopropyl-2,4,6-Trioxo-2,3,4,5,6,7-Hexahydro-1H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for modern drug discovery and development programs, particularly in oncology and antiviral research. Pharmaceutical manufacturers and research organizations require this material for its reliable quality and precise chemical functionality to ensure the integrity of their final drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule therapeutics.
• Oncology Drug Research: Used in the synthesis of targeted cancer therapies and kinase inhibitors.
• Antiviral Agent Development: Serves as a building block for compounds targeting viral replication mechanisms.
• Chemical Biology & Proteomics: Employed in the creation of specialized probes and molecular tools for target identification.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for commercial API manufacturing.
• Contract Research & Development (CRO/CDMO): Supplied to service organizations supporting global pharmaceutical pipelines.

Basic Information

Product Name	(1-Cyclopropyl-2,4,6-Trioxo-2,3,4,5,6,7-Hexahydro-1H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Acetic Acid
CAS No.	1379811-28-5
Molecular Formula	C11H11N3O5
Molecular Weight	265.22 g/mol
Synonyms	5-(Carboxymethyl)-1-cyclopropyl-2,3,4,5,6,7-hexahydro-2,4,6-trioxo-1H-pyrrolo[2,3-d]pyrimidine; 1-Cyclopropyl-2,4,6-trioxo-1,2,3,4,5,6,7-hexahydropyrrolo[2,3-d]pyrimidine-5-acetic acid; Pyrrolo[2,3-d]pyrimidine-5-acetic acid derivative; CAS 1379811-28-5; Advanced Pharmaceutical Intermediate 1379811-28-5; Cyclopropyl-pyrrolopyrimidinetrione acetic acid
EINECS	Contact for details

Quality Control

Our (1-Cyclopropyl-2,4,6-Trioxo-2,3,4,5,6,7-Hexahydro-1H-Pyrrolo[2,3-D]Pyrimidin-5-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP starting material applications. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.