Description

2-Cyclobutyl-5-Methyl[1,2,4]Triazolo-[1,5-A]Pyrimidin-7(4H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic triazolopyrimidine class. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the design and production of novel herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling production from laboratory to pilot plant and commercial manufacturing.
• Fine Chemical Production: Acts as a specialized building block for synthesizing complex, high-value molecules for various industrial applications.

Basic Information

Product Name	2-Cyclobutyl-5-Methyl[1,2,4]Triazolo-[1,5-A]Pyrimidin-7(4H)-One
CAS No.	1379811-25-2
Molecular Formula	C₁₀H₁₂N₄O
Molecular Weight	204.23 g/mol
Synonyms	2-Cyclobutyl-5-methyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one; 5-Methyl-2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one; 1379811-25-2; 2-Cyclobutyl-5-methyl-7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one; 4H-[1,2,4]Triazolo[1,5-a]pyrimidin-7-one, 2-cyclobutyl-5-methyl-; 2-Cyclobutyl-5-methyl[1,2,4]triazolopyrimidin-7-one
EINECS	Contact for details

Quality Control

Our 2-Cyclobutyl-5-Methyl[1,2,4]Triazolo-[1,5-A]Pyrimidin-7(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.