Description

2,4-Dichloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound matters because it serves as a critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists need this high-purity intermediate to accelerate their discovery and process development pipelines.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and plant growth regulators by leveraging its reactive dichloro and nitrile functionalities.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes, enzyme inhibitors, and tool compounds for biological target validation.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for conductive polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	2,4-Dichloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile
CAS No.	1379367-43-7
Molecular Formula	C7H2Cl2N4
Molecular Weight	213.02 g/mol
Synonyms	2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile; 7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 2,4-dichloro-; 2,4-Dichloropyrrolo[2,3-d]pyrimidine-5-carbonitrile; 2,4-Dichloro-5-cyanopyrrolo[2,3-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 2,4-dichloro-7H-; 1379367-43-7
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring material that meets stringent internal standards or ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.