Description

Ethyl 4-Bromopyrimidine-2-Carboxylate is a high-purity brominated pyrimidine derivative, serving as a critical building block in modern synthetic chemistry. This compound is valued for its reactive bromine substituent and ester functionality, enabling precise molecular construction. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators through structure-activity relationship (SAR) studies.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions to introduce the pyrimidine core into more complex molecules.
• Material Science: Serves as a monomer or functionalizing agent in the development of advanced organic electronic materials and ligands for catalysis.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory chemistry projects.

Basic Information

Product Name	Ethyl 4-Bromopyrimidine-2-Carboxylate
CAS No.	1379364-87-0
Molecular Formula	C7H7BrN2O2
Molecular Weight	231.05 g/mol
Synonyms	4-Bromopyrimidine-2-carboxylic acid ethyl ester; Ethyl 4-bromo-2-pyrimidinecarboxylate; 2-Pyrimidinecarboxylic acid, 4-bromo-, ethyl ester; 4-Bromo-2-(ethoxycarbonyl)pyrimidine; 1379364-87-0; Ethyl 4-bromopyrimidine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Bromopyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.