Description

2-(Bromomethyl)-4-Fluorobenzaldehyde is a versatile and high-purity fluorinated aromatic aldehyde building block. This compound is critical for the synthesis of complex molecules, offering a reactive bromomethyl handle and a formyl group for further functionalization. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that require fluorinated aromatic structures.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers where fluorine substitution modulates properties.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Chemical Biology Probes: Useful for the synthesis of fluorescent tags, affinity labels, and other molecular probes for biochemical research.

Basic Information

Product Name	2-(Bromomethyl)-4-Fluorobenzaldehyde
CAS No.	1379346-12-9
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	4-Fluoro-2-(bromomethyl)benzaldehyde; 2-Bromomethyl-4-fluorobenzaldehyde; 4-Fluoro-2-bromomethylbenzaldehyde; α-Bromo-4-fluoro-o-tolualdehyde; (2-Bromomethyl-4-fluorophenyl)methanal; 1379346-12-9; 4-Fluoro-2-(bromomethyl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 2-(Bromomethyl)-4-Fluorobenzaldehyde adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability for your critical synthesis workflows. Comprehensive analytical testing, including HPLC, GC, NMR, and MS, is performed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.