Description

4-Ethyl-2-Iodo-6-(Trifluoromethyl)Pyrimidine is a high-value, halogenated pyrimidine building block with the CAS number 1379313-78-6. This compound is specifically engineered to serve as a critical intermediate in advanced organic synthesis, offering a unique trifluoromethyl and iodo-substituted scaffold. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in creating advanced active ingredients for crop protection products, leveraging the biological activity often associated with fluorinated and halogenated heterocycles.
• Material Science Precursor: Serves as a specialized monomer or precursor for synthesizing functionalized polymers or organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex molecular architectures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Fluorine Chemistry Studies: Acts as a model compound in research focused on the introduction and reactivity of the trifluoromethyl group in heterocyclic systems.

Basic Information

Product Name	4-Ethyl-2-Iodo-6-(Trifluoromethyl)Pyrimidine
CAS No.	1379313-78-6
Molecular Formula	C7H6F3IN2
Molecular Weight	302.04 g/mol
Synonyms	2-Iodo-4-ethyl-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-4-ethyl-2-iodopyrimidine; 4-Ethyl-2-iodo-6-(trifluoromethyl)pyrimidine; 2-Iodo-4-ethyl-6-trifluoromethylpyrimidine; Pyrimidine, 4-ethyl-2-iodo-6-(trifluoromethyl)-; 1379313-78-6
EINECS	Contact for details

Quality Control

Our production of 4-Ethyl-2-Iodo-6-(Trifluoromethyl)Pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and air. Handle and store in accordance with all applicable local and international regulations for halogenated organic compounds.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.