Description

2-(Bromomethyl)-3-Fluorobenzaldehyde is a versatile and highly functionalized aromatic aldehyde building block. Its molecular structure, featuring both a reactive bromomethyl group and an aldehyde moiety on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables the synthesis of novel active ingredients through subsequent substitution and condensation reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors, where the fluorine and bromine groups modify electronic properties.
• Custom Chemical Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-(Bromomethyl)-3-Fluorobenzaldehyde
CAS No.	1379312-99-8
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	3-Fluoro-2-(bromomethyl)benzaldehyde; 2-Bromomethyl-3-fluorobenzaldehyde; 3-Fluoro-2-bromomethylbenzaldehyde; Benzaldehyde, 2-(bromomethyl)-3-fluoro-; (3-Fluoro-2-formylphenyl)methyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-3-Fluorobenzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, IR), and impurity profile is supplied with each shipment to guarantee reproducible results and process reliability for your synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from strong oxidizing agents. Due to its light-sensitive and easily oxidized nature, prolonged exposure to air and light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.