Description

4-Chloro-6-(Trifluoromethyl)Pyrimidine-2-Thiol is a high-value pyrimidine-based building block and versatile synthetic intermediate. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a critical precursor for developing advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the agrochemical and pharmaceutical industries seeking to introduce specific functional groups for enhanced bioactivity and material properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Serves as a core building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the development of specialty chemicals, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Chemical Biology: Employed as a molecular probe or linker in bioconjugation and proteomics research.
• Custom Synthesis & Scale-up: Available for contract manufacturing and custom synthesis projects from gram to multi-kilogram scale.

Basic Information

Product Name	4-Chloro-6-(Trifluoromethyl)Pyrimidine-2-Thiol
CAS No.	1379310-59-4
Molecular Formula	C5H2ClF3N2S
Molecular Weight	214.59 g/mol
Synonyms	4-Chloro-6-(trifluoromethyl)-2-pyrimidinethiol; 4-Chloro-6-(trifluoromethyl)-2-mercaptopyrimidine; 2-Mercapto-4-chloro-6-(trifluoromethyl)pyrimidine; 4-Chloro-6-trifluoromethyl-2-pyrimidinethiol; 4-Chloro-6-trifluoromethylpyrimidine-2-thiol; 2-Pyrimidinethiol, 4-chloro-6-(trifluoromethyl)-; 1379310-59-4
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Trifluoromethyl)Pyrimidine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.