Description

2,4-Dichloro-7-Fluoro-5H-Pyrrolo[3,2-D]Pyrimidine is a high-purity, multi-halogenated heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. Its core value lies in its versatile chemical structure, which serves as a privileged scaffold for the synthesis of novel, biologically active compounds. This intermediate is critically needed by R&D and process chemistry teams in the pharmaceutical industry for developing new drug candidates, particularly kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel kinase inhibitors and other small-molecule drug candidates targeting various diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated pyrrolopyrimidine core.
• Chemical Biology: Serves as a versatile scaffold for creating chemical probes and tool compounds to study biological pathways and protein functions.
• Material Science: Potential precursor for the synthesis of advanced organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploration of new heterocyclic chemistry.

Basic Information

Product Name	2,4-Dichloro-7-Fluoro-5H-Pyrrolo[3,2-D]Pyrimidine
CAS No.	1379307-68-2
Molecular Formula	C6H2Cl2FN3
Molecular Weight	205.00 g/mol
Synonyms	2,4-Dichloro-7-fluoro-5H-pyrrolo[3,2-d]pyrimidine; 7-Fluoro-2,4-dichloro-5H-pyrrolo[3,2-d]pyrimidine; 5H-Pyrrolo[3,2-d]pyrimidine, 2,4-dichloro-7-fluoro-; 2,4-Dichloro-7-fluoro-5H-pyrrolo[3,2-d]pyrimidine; 1379307-68-2; FC-1023; AKOS005258212; ZINC000103068974
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7-Fluoro-5H-Pyrrolo[3,2-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Due to its sensitivity to strong bases and fluorides, store separately from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.