Description

6-Iodothieno[2,3-D]Pyrimidin-4(3H)-One is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel kinase inhibitors and other targeted therapeutic agents. It is primarily sought by R&D departments in pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Reagent: Serves as a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine moiety.
• Biochemical Research: Employed in the development of chemical probes for studying enzyme function and cellular signaling pathways.
• Fine Chemical Production: Intermediate for the manufacture of specialized agrochemicals and materials science compounds.

Basic Information

Product Name	6-Iodothieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	1378867-62-9
Molecular Formula	C6H3IN2OS
Molecular Weight	277.07 g/mol
Synonyms	6-Iodothieno[2,3-d]pyrimidin-4(3H)-one; 6-Iodo-3H-thieno[2,3-d]pyrimidin-4-one; 6-Iodothieno[2,3-d]pyrimidin-4-ol; 4-Hydroxy-6-iodothieno[2,3-d]pyrimidine; 1378867-62-9; Thieno[2,3-d]pyrimidin-4(3H)-one, 6-iodo-; 6-Iodo-4-hydroxy-thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 6-Iodothieno[2,3-D]Pyrimidin-4(3H)-One is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to ensure long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.