Description

3-Ethoxy-5-Fluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an ethoxy and a fluorine substituent, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Functional Dye & Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments where the aldehyde group allows for further functionalization and color tuning.
• Cross-Coupling Reactions: The formyl group is amenable to various transformations, making it a valuable substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Academic & Contract Research: Utilized in research laboratories for method development and exploring new synthetic pathways in fluorine chemistry.

Basic Information

Item	Detail
Product Name	3-Ethoxy-5-Fluorobenzaldehyde
CAS No.	1378670-41-7
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	5-Fluoro-3-ethoxybenzaldehyde; 3-Ethoxy-5-fluorobenzenecarboxaldehyde; 1-Ethoxy-3-fluoro-5-formylbenzene; m-Ethoxy-m-fluorobenzaldehyde; 5-Fluoro-3-ethoxy-benzaldehyde; Benzaldehyde, 3-ethoxy-5-fluoro-
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-5-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.