Description

2,4-Difluoro-5-Methylaniline is a fluorinated aniline derivative, a key building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for introducing specific fluorine-substituted aromatic motifs into target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluoromethylaniline moiety to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Can be incorporated as a monomer or modifier to create specialty polymers with unique thermal and chemical resistance properties.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of complex, high-performance dyes and pigments.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	2,4-Difluoro-5-Methylaniline
CAS No.	1378579-56-6
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	5-Methyl-2,4-difluoroaniline; 2,4-Difluoro-5-methylbenzenamine; 1-Amino-2,4-difluoro-5-methylbenzene; Benzenamine, 2,4-difluoro-5-methyl-; 5-Methyl-2,4-difluorobenzenamine; 2,4-Difluoro-5-methyl-phenylamine; 2,4-DFMA
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Methylaniline is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.