Description

3,6-Difluoro-2-Methylbenzaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the reactive aldehyde group, enabling precise molecular modifications to enhance the properties of target compounds. This intermediate is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics where fluorine substitution is used to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides, fungicides, and pesticides, where the difluoromethylbenzene core contributes to efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs), where fluorine atoms improve charge transport and stability.
• Specialty Polymer Monomer: Functions as a building block for high-performance polymers, including polyimides and epoxy resins, imparting enhanced thermal stability and chemical resistance.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a versatile reagent for exploring new reactions and creating complex molecular architectures via cross-coupling and condensation reactions.

Basic Information

Product Name	3,6-Difluoro-2-Methylbenzaldehyde
CAS No.	1378525-21-3
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	2,5-Difluoro-6-methylbenzaldehyde; 2-Methyl-3,6-difluorobenzaldehyde; 3,6-Difluoro-o-tolualdehyde; 2,5-Difluoro-6-formyltoluene; 6-Methyl-2,5-difluorobenzaldehyde; Benzaldehyde, 3,6-difluoro-2-methyl-; 1378525-21-3 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 3,6-Difluoro-2-Methylbenzaldehyde is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the high standards required for advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.