Description

Methyl 2-Aminopyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its multifunctional pyrazolopyrimidine scaffold, which serves as a privileged structure for developing novel bioactive molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the discovery and optimization of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting the pyrazolopyrimidine pharmacophore.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic framework.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes to study enzyme function and cellular signaling pathways.
• Material Science Research: Investigated as a potential building block for organic electronic materials and metal-organic frameworks (MOFs) due to its conjugated system and coordination sites.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	Methyl 2-Aminopyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	1375087-39-0
Molecular Formula	C8H8N4O2
Molecular Weight	192.18 g/mol
Synonyms	Methyl 2-aminopyrazolo[1,5-a]pyrimidine-3-carboxylate; 2-Amino-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid methyl ester; Methyl 2-amino-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylate; 3-Carbomethoxy-2-aminopyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 2-amino-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Aminopyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.