Description

5-Bromo-2,3-difluoroaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the aromatic ring, enabling precise molecular modifications and the introduction of unique electronic properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediates: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine substituents enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for functional dyes, liquid crystals, and organic electronic materials due to its ability to fine-tune optical and electronic properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, facilitating complex molecule assembly.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and synthesizing novel fluorinated aromatic compounds.

Basic Information

Product Name	5-Bromo-2,3-difluoroaniline
CAS No.	1375068-68-0
Molecular Formula	C6H4BrF2N
Molecular Weight	208.00 g/mol
Synonyms	2,3-Difluoro-5-bromoaniline; 5-Bromo-2,3-difluorobenzenamine; Benzenamine, 5-bromo-2,3-difluoro-; 5-Bromo-2,3-difluoro-phenylamine; 2,3-Difluoro-5-bromo-phenylamine; 5-Bromo-2,3-difluoroaniline (primary name)
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-difluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.