Description

Pyrimidine, 5-Bromo-2-(Pyrrolidin-3-Ylmethyl)- is a high-value, heterocyclic organic compound featuring a pyrimidine core substituted with bromine and a pyrrolidinylmethyl group. This specific molecular architecture makes it a critical building block (synthon) in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D and process chemistry teams for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals. The compound's utility stems from its role as a versatile intermediate for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the research and development of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Medicinal Chemistry: Serves as a core scaffold for designing and synthesizing chemical probes and libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science Research: Potential building block for advanced organic electronic materials or metal-organic frameworks (MOFs) due to its nitrogen-rich, aromatic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for client projects.

Basic Information

Product Name	Pyrimidine, 5-Bromo-2-(Pyrrolidin-3-Ylmethyl)-
CAS No.	1375065-24-9
Molecular Formula	C9H12BrN3
Molecular Weight	242.12 g/mol
Synonyms	5-Bromo-2-[(pyrrolidin-3-yl)methyl]pyrimidine; 2-((Pyrrolidin-3-yl)methyl)-5-bromopyrimidine; 5-Bromo-2-(pyrrolidin-3-ylmethyl)pyrimidine; 5-Bromo-2-(3-pyrrolidinylmethyl)pyrimidine; 1375065-24-9; 5-Bromo-2-(pyrrolidin-3-ylmethyl)pyrimidine; 5-Bromo-2-(3-pyrrolidinylmethyl)-pyrimidine
EINECS	Contact for details

Quality Control

Our production of Pyrimidine, 5-Bromo-2-(Pyrrolidin-3-Ylmethyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up work. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with ISO 9001 quality management standards and can provide material suitable for use under GMP (Good Manufacturing Practice) guidelines for investigational products upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.