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2-Methylsulfanyl-5,6,7,8-Tetrahydro-Pyrido[3,2-D]Pyrimidine Hydrochloride CAS NO 1375064-63-3


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CAS No.:1375064-63-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Methylsulfanyl-5,6,7,8-Tetrahydro-Pyrido[3,2-D]Pyrimidine Hydrochloride is a high-purity, heterocyclic organic compound offered as a hydrochloride salt for enhanced stability and handling. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted small-molecule drugs.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for oncology and CNS disorders.
  • Kinase Inhibitor Research: Serves as a core scaffold or precursor in the development of potent and selective kinase inhibitors.
  • Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization processes.
  • Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production of active pharmaceutical ingredients (APIs).
  • Academic Research: Utilized in university and institutional laboratories for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name 2-Methylsulfanyl-5,6,7,8-Tetrahydro-Pyrido[3,2-D]Pyrimidine Hydrochloride
CAS No. 1375064-63-3
Molecular Formula C9H12N3S·HCl
Molecular Weight 229.73 g/mol
Synonyms 5,6,7,8-Tetrahydro-2-(methylthio)pyrido[3,2-d]pyrimidine hydrochloride; 2-(Methylthio)-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidine hydrochloride; 2-Methylsulfanyl-5,6,7,8-tetrahydro-pyrido[3,2-d]pyrimidine HCl; Pyrido[3,2-d]pyrimidine, 5,6,7,8-tetrahydro-2-(methylthio)-, hydrochloride; 1375064-63-3; UNII-9F8Q3V2Q0N
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Quality Control

Our 2-Methylsulfanyl-5,6,7,8-Tetrahydro-Pyrido[3,2-D]Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to reference spectrum
Assay (HPLC) ≥98.0%
Water Content (KF) ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm
Single Unknown Impurity (HPLC) ≤0.5%
Total Impurities (HPLC) ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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