Description

3-Fluoro-4-(Hydroxymethyl)Phenyl Acetate is a high-value fluorinated aromatic building block and intermediate. This compound matters for its role in synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for modulating bioactivity and metabolic stability. It is primarily needed by research chemists and process development scientists in pharmaceutical R&D, agrochemical discovery, and advanced material science for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where fluorinated aromatic structures enhance efficacy.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated phenyl acetate groups into polymer chains, altering material properties like solubility and thermal stability.
• Chemical Research & Development: A versatile starting material for academic and industrial research in organic synthesis and medicinal chemistry.
• Fluorine-18 Radiochemistry: Potential precursor for the synthesis of PET (Positron Emission Tomography) imaging agents, given its fluorinated aromatic structure.

Basic Information

Product Name	3-Fluoro-4-(Hydroxymethyl)Phenyl Acetate
CAS No.	1374652-10-4
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	4-(Acetoxymethyl)-2-fluorophenol; 2-Fluoro-4-hydroxybenzyl acetate; (3-Fluoro-4-hydroxyphenyl)methyl acetate; 1-(Acetoxymethyl)-2-fluoro-4-hydroxybenzene; 4-Hydroxy-3-fluorobenzyl acetate; Acetic acid (3-fluoro-4-hydroxybenzyl) ester; 2-Fluoro-4-(hydroxymethyl)phenyl acetate
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Hydroxymethyl)Phenyl Acetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.