Description

(2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-D]Pyrimidin-6-Yl)Methanol is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is essential for research and development organizations, pharmaceutical manufacturers, and fine chemical suppliers engaged in the production of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for oncology and other therapeutic areas.
• Kinase Inhibitor Development: Core scaffold for the research and production of potent and selective kinase inhibitors, targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new drug candidates.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production of clinical trial materials and commercial APIs.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Fine Chemical Synthesis: Utilized in the preparation of more complex, functionalized pyrrolopyrimidine derivatives for specialized applications.

Basic Information

Product Name	(2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-D]Pyrimidin-6-Yl)Methanol
CAS No.	1374639-77-6
Molecular Formula	C₁₂H₁₄ClN₃O
Molecular Weight	251.71 g/mol
Synonyms	6-(Hydroxymethyl)-2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine; (2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol; 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol; 1374639-77-6; 2-Chloro-7-cyclopentyl-6-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our (2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-D]Pyrimidin-6-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with complete analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.