Description

7-Bromo-6-Fluoroquinazoline-2,4(1H,3H)-Dione is a high-purity, halogenated quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, particularly for applications requiring a specific bromo-fluoro substitution pattern.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme function and cellular pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	7-Bromo-6-Fluoroquinazoline-2,4(1H,3H)-Dione
CAS No.	1374208-43-1
Molecular Formula	C8H4BrFN2O2
Molecular Weight	259.03 g/mol
Synonyms	7-Bromo-6-fluoro-1H,3H-quinazoline-2,4-dione; 7-Bromo-6-fluoroquinazoline-2,4-diol; 2,4-Dihydroxy-7-bromo-6-fluoroquinazoline; 7-Bromo-6-fluoro-2,4(1H,3H)-quinazolinedione; 1374208-43-1; 7-Br-6-F-quinazoline-2,4-dione
EINECS	Contact for details

Quality Control

Every batch of 7-Bromo-6-Fluoroquinazoline-2,4(1H,3H)-Dione is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.