Description

1-[3-(Trifluoromethoxy)Phenyl]Ethan-1-Amine Hydrochloride is a high-purity, fluorinated aromatic amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. This compound is valued for its trifluoromethoxy group, which imparts unique electronic and metabolic properties to target molecules, enhancing their lipophilicity and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutic agents where the trifluoromethoxy moiety is beneficial.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the chemical stability and biological activity of the fluorinated aromatic structure.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and in materials science research for creating novel functional molecules.
• Chemical Synthesis Building Block: Utilized in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies to improve drug candidate profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-[3-(Trifluoromethoxy)Phenyl]Ethan-1-Amine Hydrochloride
CAS No.	1373925-07-5
Molecular Formula	C9H9F3NO•HCl
Molecular Weight	243.63 g/mol
Synonyms	1-[3-(Trifluoromethoxy)phenyl]ethanamine hydrochloride; α-Methyl-3-(trifluoromethoxy)benzylamine hydrochloride; 1-(3-Trifluoromethoxyphenyl)ethylamine HCl; 3-(Trifluoromethoxy)phenethylamine hydrochloride (isomer); (RS)-1-[3-(Trifluoromethoxy)phenyl]ethanamine hydrochloride; 1-(3-(Trifluoromethoxy)phenyl)ethan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethoxy)Phenyl]Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results. We adhere to cGMP standards where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.