Description

2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzyl Bromide, 97% is a high-purity, multi-functional organic building block essential for advanced chemical synthesis. Its value lies in the strategic combination of fluorine, methoxy, and trifluoromethyl substituents on a benzyl bromide core, enabling precise molecular modifications. This compound is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for synthesizing fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: The reactive benzyl bromide moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems.
• Functional Material Research: Employed in the synthesis of specialty polymers, ligands for catalysis, and advanced organic frameworks with tailored properties.

Basic Information

Product Name	2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzyl Bromide, 97%
CAS No.	1373921-05-1
Molecular Formula	C10H7BrF4O
Molecular Weight	299.06 g/mol
Synonyms	1-(Bromomethyl)-2-fluoro-5-methoxy-3-(trifluoromethyl)benzene; α-Bromo-2-fluoro-5-methoxy-α,α,α-trifluoro-m-xylene; 2-Fluoro-5-methoxy-α,α,α-trifluoro-m-tolyl bromide; (2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl)methyl bromide; 3-(Bromomethyl)-6-fluoro-1-methoxy-5-(trifluoromethyl)benzene; 2-Fluoro-5-methoxy-3-trifluoromethylbenzyl bromide; 2-Fluoro-5-methoxy-alpha,alpha,α-trifluoro-m-tolyl bromide
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure the 97% minimum purity and identity are consistently met. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.